Publications CVON-Reconnect

  • Paulus WJ1, Dal Canto E2. Distinct Myocardial Targets for Diabetes Therapy in Heart Failure With Preserved or Reduced Ejection Fraction. JACC Heart Fail. 2018 Jan;6(1):1-7. PMID: 29284577.

  • Gremmels H1, Joles JA. Fibrates in hypertension: where do we stand? J Hypertens. 2018 May;36(5):1024-1028. PMID: 29578959.
  • Brandt MM1, Meddens CA2,3, Louzao-Martinez L4, van den Dungen NAM5,6, Lansu NR2,3,6, Nieuwenhuis EES2, Duncker DJ1, Verhaar MC4, Joles JA4, Mokry M2,3,6, Cheng C7,4. Chromatin Conformation Links Distal Target Genes to CKD Loci. J Am Soc Nephrol. 2018 Feb;29(2):462-476. PMID: 29093029.

  • Wesseling M1, van Koeverden ID1, van Lammeren GW2, van der Laan SW1, Haitjema S1, de Vries JPM2, den Ruijter HM1, de Jager SCA1, Hoefer I1, Blankestijn P3, Verhaar M3, de Kleijn DPV4, de Borst GJ4, Pasterkamp G5. Impaired kidney function is associated with intraplaque hemorrhage in patients undergoing carotid endarterectomy. Atherosclerosis. 2017 Nov;266:128-135. PMID: 29024865.

  • Kievit RF1, Gohar A1,2, Hoes AW1, Bots ML1, van Riet EE1, van Mourik Y1, Bertens LC1, Boonman-de Winter LJ1,3, den Ruijter HM2, Rutten FH1; Queen of Hearts and RECONNECT consortium. Efficient selective screening for heart failure in elderly men and women from the community: A diagnostic individual participant data meta-analysis. Eur J Prev Cardiol. 2018 Mar;25(4):437-446. PMID: 29327942.

  • Ter Maaten JM1, Voors AA2, Damman K1, van der Meer P1, Anker SD3, Cleland JG4, Dickstein K5, Filippatos G6, van der Harst P1, Hillege HL1, Lang CC7, Metra M8, Navis G9, Ng L10, Ouwerkerk W11, Ponikowski P12, Samani NJ10, van Veldhuisen DJ1, Zannad F13, Zwinderman AH11, de Borst MH9. Fibroblast growth factor 23 is related to profiles indicating volume overload, poor therapy optimization and prognosis in patients with new-onset and worsening heart failure. Int J Cardiol. 2018 Feb 15;253:84-90. PMID: 29306478.

  • van Essen GJ1, Te Lintel Hekkert M1, Sorop O1, Heinonen I1,2, van der Velden J3,4, Merkus D1, Duncker DJ5,6. Cardiovascular Function of Modern Pigs Does not Comply with Allometric Scaling Laws. Sci Rep. 2018 Jan 15;8(1):792. PMID: 29335617.

  • Sorop O1, Heinonen I1,2, van Kranenburg M1,3, van de Wouw J1, de Beer VJ1, Nguyen ITN4, Octavia Y1, van Duin RWB1, Stam K1, van Geuns RJ1,3, Wielopolski PA3, Krestin GP3, van den Meiracker AH5, Verjans R6, van Bilsen M6,7, Danser AHJ5, Paulus WJ8, Cheng C1,4, Linke WA9, Joles JA4, Verhaar MC4, van der Velden J8,10, Merkus D1, Duncker DJ1,10. Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening. Cardiovasc Res. 2018 Jun 1;114(7):954-964. PMID: 29432575.

  • van den Dorpel MMP1, Heinonen I1,2,3, Snelder SM4, Vos HJ5, Sorop O1, van Domburg RT1, Merkus D1, Duncker DJ1, van Dalen BM6,7. Early detection of left ventricular diastolic dysfunction using conventional and speckle tracking echocardiography in a large animal model of metabolic dysfunction. Int J Cardiovasc Imaging. 2018 May;34(5):743-749. PMID: 29234934.

  • De Haan JJ1, Haitjema S1, den Ruijter HM1, Pasterkamp G1,2, de Borst GJ3, Teraa M3, Verhaar MC4, Gremmels H4, de Jager SCA5,6. Growth Differentiation Factor 15 Is Associated With Major Amputation and Mortality in Patients With Peripheral Artery Disease. J Am Heart Assoc. 2017 Aug 30;6(9). PMID: 28855167.

  • Badimon L1,2, Bugiardini R3, Cenko E3, Cubedo J4, Dorobantu M5, Duncker DJ6, Estruch R7,8, Milicic D9, Tousoulis D10, Vasiljevic Z11, Vilahur G4, de Wit C12, Koller A13,14. Position paper of the European Society of Cardiology-working group of coronary pathophysiology and microcirculation: obesity and heart disease. Eur Heart J. 2017 Jul 1;38(25):1951-1958. PMID: 28873951.
  • Binnenmars SH1, Hijmans RS1, Navis G1, de Borst MH1. Biomarkers of Renal Function: Towards Clinical Actionability. Clin Pharmacol Ther. 2017 Sep;102(3):481-492. PMID: 28608458.

  • Zhou Z1,2, Sorop O1, de Beer VJ1, Heinonen I1,3,4, Cheng C1,5, Jan Danser AH6, Duncker DJ1, Merkus D7. Altered purinergic signaling in uridine adenosine tetraphosphate-induced coronary relaxation in swine with metabolic derangement. Purinergic Signal. 2017 Sep;13(3):319-329. PMID: 28540569.

  • Sorop O1, Olver TD2, van de Wouw J1, Heinonen I3, van Duin RW1,4, Duncker DJ1, Merkus D1. The microcirculation: a key player in obesity-associated cardiovascular disease. Cardiovasc Res. 2017 Jul 1;113(9):1035-1045. PMID: 28482008.

  • Pei J1, Harakalova M2, den Ruijter H3, Pasterkamp G3, Duncker DJ4, Verhaar MC1, Asselbergs FW5, Cheng C6. Cardiorenal disease connection during post-menopause: The protective role of estrogen in uremic toxins induced microvascular dysfunction. Int J Cardiol. 2017 Jul 1;238:22-30. PMID: 28341374.

  • Oosterhuis NR1, Bongartz LG1,2, Verhaar MC1, Cheng C1,3, Xu YJ1, van Koppen A1, Cramer MJ2, Goldschmeding R4, Gaillard CA5, Doevendans PA2, Braam B6, Joles JA1. Targeting multiple pathways reduces renal and cardiac fibrosis in rats with subtotal nephrectomy followed by coronary ligation. Acta Physiol (Oxf). 2017 Jul;220(3):382-393. PMID: 28168814.

  • Paulus WJ1. Turning the Retrospectroscope on Heart Failure With Preserved Ejection Fraction. J Card Fail. 2016 Dec;22(12):1023-1027. PMID: 27697502.
  • Bender SB1,2,3, de Beer VJ4, Tharp DL5, Bowles DK5,6,7, Laughlin MH5,6,7, Merkus D4, Duncker DJ4. Severe familial hypercholesterolemia impairs the regulation of coronary blood flow and oxygen supply during exercise. Basic Res Cardiol. 2016 Nov;111(6):61. PMID: 27624732.

  • Sorop O1,2, van den Heuvel M1,3, van Ditzhuijzen NS1, de Beer VJ1, Heinonen I1, van Duin RW1, Zhou Z1, Koopmans SJ4, Merkus D1, van der Giessen WJ1,2, Danser AH3, Duncker DJ5. Coronary microvascular dysfunction after long-term diabetes and hypercholesterolemia. Am J Physiol Heart Circ Physiol. 2016 Dec 1;311(6):H1339-H1351. PMID: 27591223.

  • Louzao-Martinez L1, Vink A2, Harakalova M3, Asselbergs FW4, Verhaar MC5, Cheng C6. Characteristic adaptations of the extracellular matrix in dilated cardiomyopathy. Int J Cardiol. 2016 Oct 1;220:634-46. PMID: 27391006.

  • Shah SJ1, Kitzman DW1, Borlaug BA1, van Heerebeek L1, Zile MR1, Kass DA1, Paulus WJ2. Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction: A Multiorgan Roadmap. Circulation. 2016 Jul 5;134(1):73-90. PMID: 27358439.

  • El Azzouzi H1, Doevendans PA1, Sluijter JP1. Long non-coding RNAs in heart failure: an obvious lnc. Ann Transl Med. 2016 May;4(9):182. PMID: 27275495.

  • van Dijk CG1, Oosterhuis NR1, Xu YJ1, Brandt M1, Paulus WJ1, van Heerebeek L1, Duncker DJ1, Verhaar MC1, Fontoura D1, Lourenço AP1, Leite-Moreira AF1, Falcão-Pires I1, Joles JA1, Cheng C2. Distinct Endothelial Cell Responses in the Heart and Kidney Microvasculature Characterize the Progression of Heart Failure With Preserved Ejection Fraction in the Obese ZSF1 Rat With Cardiorenal Metabolic Syndrome. Circ Heart Fail. 2016 Apr;9(4):e002760. PMID: 27056881.

  • Ter Maaten JM1, Damman K1, Verhaar MC2, Paulus WJ3, Duncker DJ4, Cheng C2,4, van Heerebeek L3, Hillege HL5, Lam CS6, Navis G7, Voors AA1. Connecting heart failure with preserved ejection fraction and renal dysfunction: the role of endothelial dysfunction and inflammation. Eur J Heart Fail. 2016 Jun;18(6):588-98. PMID: 26861140.

  • Heinonen I1, Sorop O2, de Beer VJ2, Duncker DJ2, Merkus D3. What can we learn about treating heart failure from the heart’s response to acute exercise? Focus on the coronary microcirculation. J Appl Physiol (1985). 2015 Oct 15;119(8):934-43. PMID: 26048972.

  • Khairoun M1, van den Heuvel M2, van den Berg BM3, Sorop O2, de Boer R1, van Ditzhuijzen NS2, Bajema IM4, Baelde HJ4, Zandbergen M4, Duncker DJ2, Rabelink TJ3, Reinders ME3, van der Giessen WJ2, Rotmans JI3. Early systemic microvascular damage in pigs with atherogenic diabetes mellitus coincides with renal angiopoietin dysbalance. PLoS One. 2015 Apr 24;10(4):e0121555. PMID: 25909188.